EvoPatchTM
Purpose-built amnion coverage for the surgical healing environment.
EvoPatch is a sterile, dehydrated human amniotic membrane allograft constructed with two layers of amnion and no chorion.
Designed for robotic, laparoscopic, and open surgical workflows, EvoPatch provides protective human tissue coverage where the clinician determines that additional wound covering is appropriate.
Two layers of amnion. No side selection. One deliberate surgical platform.
Not Just a Sheet. A Purpose-Built Amnion Platform.
Surgical tissue coverings have traditionally included synthetic films, absorbable barriers, hydrogels, collagen products, and human tissue allografts. EvoPatch begins with human amniotic membrane.
Protective coverage, built around the biology and realities of surgery.
Human tissue architecture
Derived from donated human amniotic membrane rather than a synthetic polymer or animal-derived material.
Amnion-on-amnion construction
Two layers of amnion form a single surgical covering.
No orientation decision
The omni-directional design eliminates the need to identify a maternal or fetal side during placement.
Designed for surgical access
Configurations support placement through robotic, laparoscopic, and open approaches.
Human Amniotic Membrane, Engineered as a Surgical Covering
EvoPatch is a sterile, dehydrated human amniotic membrane allograft intended for use as a wound covering.
Its dual-layer construction provides a broad, continuous tissue format that can be selected according to the anatomy, procedural approach, and area requiring coverage.
EvoPatch can be placed dry or hydrated with sterile saline at the discretion of the healthcare provider. It is packaged for single-patient use and stored at ambient temperature.
Two Layers of Amnion
EvoPatch uses an amnion-on-amnion configuration rather than an amnion-chorion laminate.
Chorion-Free
The graft contains human amniotic membrane without an incorporated chorion layer.
Omni-Directional
Either surface may face the treatment site, simplifying orientation during placement.
Broad Sheet Coverage
The sheet format supports tissue planes, surgical sites, and anatomical surfaces where a flat graft is appropriate.
The First Days After Surgery Can Shape the Tissue Response
Surgical injury initiates a coordinated sequence involving coagulation, fibrin formation, inflammatory signaling, immune-cell recruitment, fibroblast activity, extracellular-matrix deposition, fibrinolysis, and tissue remodeling.
Tissue Injury
Surgical dissection disrupts the mesothelial surface and exposes the underlying extracellular matrix.
Fibrin and Inflammatory Signaling
Coagulation and inflammatory pathways respond rapidly as immune-cell recruitment begins.
Repair or Fibrotic Bridging
Fibroblasts and immune cells enter the site. Fibrin may be cleared or organized into collagen-rich fibrotic tissue.
Surface Restoration
Mesothelial recovery and balanced matrix remodeling help re-establish a functional tissue surface.
Coverage During a Biologically Active Interval
EvoPatch is designed to provide protective tissue coverage during the early postoperative environment. It should not be described merely as material placed at the end of a procedure. It is a surgical tissue platform positioned at the intersection of anatomy, timing, and healing biology.
Designed Around Both Tissue and Technique
EvoPatch brings together human amniotic membrane, dual-layer construction, omni-directional placement, and practical OR handling.
Dual-Layer Architecture
Two layers of human amnion create the EvoPatch sheet configuration.
Thin, Flexible Profile
Designed to adapt to surgical anatomy without the bulk associated with thicker multilayer materials.
Omni-Directional Placement
No maternal-side or fetal-side identification is required.
Broad Configuration Range
Multiple dimensions allow clinicians to select coverage appropriate to the procedural site.
Dry or Hydrated Handling
EvoPatch may be placed directly from the sterile package or hydrated with sterile saline.
Ambient Storage
Stored in a clean, dry environment at 15-30°C. No refrigeration is required.
Building the Evidence Behind the Tissue
EvoPatch is part of an expanding scientific program examining how human amniotic membrane interacts with the postoperative environment.
Local inflammatory signaling
Macrophage behavior
Tissue-plane preservation
Collagen organization
Material persistence and transformation
Clinical translation
From Observation to Mechanism
Encouraging preclinical and retrospective observations are informing ongoing translational research. The numerical findings belong in a dedicated evidence page with study design, limitations, disclosures, and data-on-file language.
Preclinical and retrospective findings are investigational and should not be interpreted as establishing comparative clinical effectiveness. Controlled human studies are required to confirm clinical outcomes.
Completed and Active Foundations
Mechanistic evaluation, murine adhesion modeling, and retrospective gastrointestinal review.
Translational Development
Large-animal gastrointestinal research and pelvic or gynecologic adhesion development.
Prospective Evaluation
Future studies may assess adhesion incidence, severity, safety, material persistence, and tissue response.
Broad Coverage for Diverse Surgical Environments
EvoPatch may be considered when a licensed clinician determines that additional wound covering is appropriate, consistent with the Instructions for Use, patient presentation, institutional protocol, and surgical judgment.
Colorectal and Gastrointestinal
- Lower anterior resection
- Colectomy and bowel resection
- Primary intestinal anastomosis
- Rectal stump procedures
- Adhesiolysis
Obstetrics and Gynecology
- Endometriosis resection
- Myomectomy
- Hysterectomy
- Oophorectomy
- Pelvic adhesiolysis
Urology
- Robotic or laparoscopic prostatectomy
- Urethral reconstruction
- Stricture procedures
- Fistula-repair environments
General and Surgical Oncology
- Breast procedures
- Hernia procedures
- Abdominal and pelvic oncology
- Pancreatic procedures
Cardiothoracic, Thoracic, and Vascular
- Pericardial coverage
- Sternal-edge coverage
- Conduit-harvest sites
- Esophagectomy
- Lobectomy
Procedure examples are informational and should not imply a particular clinical outcome.
A Surgical Tissue Platform, Ready When Needed
EvoPatch is designed for clinical handling, practical inventory management, and straightforward documentation.
Donated Human Amniotic Membrane
Processed from donated human placental tissue.
Double-Layer Construction
Two layers of amnion form the finished graft.
Chorion-Free
No chorion layer is incorporated into the product.
Sterile
Final product sterilization is performed using gamma irradiation according to the current IFU.
Single-Patient Use
EvoPatch must not be reused or re-sterilized.
Dry or Hydrated Handling
EvoPatch may be placed directly from the sterile package or hydrated with sterile saline.
Natural Tissue Variation
Color may vary from white or off-white to pale yellow, opaque, or light brown.
Tissue Traceability
Allograft identification, size, product code, and expiration information support tracking.
Coverage From Focused Sites to Broad Surgical Fields
EvoPatch is available in a range of dimensions, allowing clinicians and facilities to match the graft configuration to anatomy and procedural requirements.
| SKU | Product | Size |
|---|---|---|
| EAP-11 | EvoPatch Amnion Graft Double-Layer | 1×1 cm |
| EAP-22 | EvoPatch Amnion Graft Double-Layer | 2×2 cm |
| EAP-23 | EvoPatch Amnion Graft Double-Layer | 2×3 cm |
| EAP-24 | EvoPatch Amnion Graft Double-Layer | 2×4 cm |
| EAP-35 | EvoPatch Amnion Graft Double-Layer | 3×5 cm |
| EAP-44 | EvoPatch Amnion Graft Double-Layer | 4×4 cm |
| EAP-46 | EvoPatch Amnion Graft Double-Layer | 4×6 cm |
| EAP-46B | EvoPatch Amnion Graft Double-Layer | 4×6 cm Butterfly |
| EAP-48 | EvoPatch Amnion Graft Double-Layer | 4×8 cm |
| EAP-66 | EvoPatch Amnion Graft Double-Layer | 6×6 cm End-to-End |
| EAP-67 | EvoPatch Amnion Graft Double-Layer | 6×7 cm |
| EAP-1010 | EvoPatch Amnion Graft Double-Layer | 10×10 cm |
| EAP-0612 | EvoPatch Amnion Graft Double-Layer | 6×12 cm |
| EAP-0212 | EvoPatch Amnion Graft Double-Layer | 2×12 cm |
Simple Steps. Deliberate Placement.
Always follow the current product Instructions for Use.
Inspect
Confirm packaging integrity and expiration date.
Open
Use sterile technique and deliver the sterile inner pouch to the sterile field.
Remove
Carefully remove EvoPatch from the inner pouch.
Prepare
Use dry or hydrate with sterile saline at clinician discretion.
Place
Position the graft over the area where protective wound coverage is appropriate.
Document
Record the allograft identification and relevant procedural information.
Designed for Real Operating-Room Logistics
EvoPatch supports practical inventory management and procedural readiness.
- Ambient-temperature storage
- No refrigeration required
- Compact sterile packaging
- Multiple surgical configurations
- Dry presentation
- Optional saline hydration
- No side-orientation requirement
- Single-patient use
- Lot and expiration traceability
- Product education available from Evologics
Frequently Asked Questions
Human Tissue, Responsibly Presented
EvoPatch is a human cells, tissues, and cellular and tissue-based product, or HCT/P.
Evologics has determined that EvoPatch meets the criteria for regulation solely under Section 361 of the Public Health Service Act and 21 CFR Part 1271. The product is minimally manipulated and intended for homologous use.
EvoPatch has not been cleared or approved by the U.S. Food and Drug Administration. FDA establishment registration or HCT/P listing does not constitute FDA approval or a determination of regulatory compliance.
Use must be consistent with the current Instructions for Use, applicable labeling, clinician judgment, and institutional protocol.
Give the Surgical Site More Than Coverage Alone
EvoPatch brings together human amniotic membrane, double-layer construction, omni-directional placement, and a growing scientific program in one surgical tissue platform.
Request EvoPatch Information
Complete the form and an Evologics representative will follow up with product materials, available configurations, institutional-review documentation, and next steps.
Regulated under Section 361 of the Public Health Service Act and 21 CFR Part 1271.
Protective human tissue coverage with active evidence development.
Product education, sizing information, and operational support for surgical workflows.